It is believed that as much as 95% of the population have encountered Epstein-Barr (EBV) also known as Human Herpes Virus 4 (HHV-4) at some point in their life. EBV can hide itself in the B lymphocyte cells of the body which allows the infection to go dormant and in many cases, remain dormant for the remainder of the hosts life. Most cases of EBV are transmitted through saliva and can take about a month to show symptoms but many cases never develop symptoms, during that time frame it can be transmitted to other people. In most cases symptoms will never present, but in 30-50% of patients this infection will lead to “mono” and compromise the immune system. When EBV is present in patients with Lyme Disease or Autoimmune diseases like Chronic Fatigue Syndrome or Fibromyalgia, it is crucial to test for EBV and treat as necessary as there could be a relationship between the two.

Symptoms of Epstein Barr

·         Mild fever

·         Sore throat

·         Swollen lymph nodes

·         Prolonged Fatigue

·         Spleen enlargement

·         Jaundice

·         Lack of appetite

·         Weakness & Sore Muscles



The surprising similarity in symptoms between EBV and other autoimmune diseases as well as Lyme Disease can be seen in the graphic above. New research is being conducted on EBV and other viruses that may be activated by the presence of Lyme Disease and/or other autoimmune diseases. The combination of infection results in accelerated debilitating symptoms such as extreme fatigue and a host of other neurological and autoimmune symptoms. 

“Some diseases have stronger links than others; yet, there are few autoimmune conditions in which EBV isn’t considered to have a role.”


If you are currently experiencing fatigue, or have been diagnosed with an Autoimmune Disease or Lyme Disease and other co-infections, you may want to discuss further testing with your Doctor. Lyme Disease is known as “the great imitator and is often over looked because so many different conditions stem from it; research is beginning to point to EBV being a big underlying factor with Autoimmune diseases. Everything is inner linked, if you only look at one piece of the puzzle, you won’t be able to put it together. I encourage you to seek proper diagnosis and further your understanding of what it takes to get to that path of wellness. To learn more, click here.